Thanks to antilles for the following.
Ana Lucia's traffic stop in "The Lie." The road Hurley's on when he pulls over is drastically different from the road he's on when he pulls away. It goes from a busy four-lane road to a two-lane road. The same blue truck appears behind his car in both shots, but the license plate numbers are different before and after the stop.
(I requested a screencap b/c I don't have one, but thought it was more appropriate as a continuity error.)